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CANCARE connects clinicians, researchers and trainees to improve care for critically ill cardiovascular patients through collaboration, shared learning and research.
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Concise summaries, clinical context and links to the original research.
Clinical takeaway The pooled findings support a haemodynamic signal for istaroxime, but do not establish a patient-centred outcome benefit. Clinical outcome effects require confirmation in a phase III trial.
Clinical takeaway Age of 80 years or older was associated with higher in-hospital mortality in PCI-treated infarction-related cardiogenic shock. These data do not establish that the association differs by out-of-hospital cardiac arrest status.
Clinical takeaway The pooled evidence suggests longer ICU stays with catheter-directed thrombolysis, without a statistically significant mortality or major bleeding difference. These findings do not establish equivalence between treatments.
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