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CANCARE connects clinicians, researchers and trainees to improve care for critically ill cardiovascular patients through collaboration, shared learning and research.
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Concise summaries, clinical context and links to the original research.
Clinical takeaway Pre-ECMO laboratory abnormalities were associated with hospital mortality, but these exploratory findings do not establish biomarker-based candidacy criteria or causal effects.
Clinical takeaway Vasodilation and myocardial dysfunction were associated with early postoperative hypotension in this vascular-surgery cohort. These findings describe potential haemodynamic contributors rather than establish causation or benefits from targeted treatment.
Clinical takeaway The pooled findings support a haemodynamic signal for istaroxime, but do not establish a patient-centred outcome benefit. Clinical outcome effects require confirmation in a phase III trial.
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A future collection of important trials in cardiovascular critical care.
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