This multicentre registry analysis examined 658 patients with acute myocardial infarction-related cardiogenic shock undergoing PCI, including 177 aged 80 years or older. Overall, 279 patients (42.4%) died during hospitalization. Octogenarian status was associated with higher adjusted odds of in-hospital mortality (adjusted OR 2.14; 95% CI 1.32–3.48). The association was statistically significant among patients without out-of-hospital cardiac arrest but not among those with arrest; however, the interaction was not significant (P=0.422), leaving differences by arrest status unproven and the stratified findings hypothesis-generating.
Age of 80 years or older was associated with higher in-hospital mortality in PCI-treated infarction-related cardiogenic shock. These data do not establish that the association differs by out-of-hospital cardiac arrest status.
Study limitation: Observational associations cannot establish causality, and the nonsignificant interaction limits interpretation of arrest-stratified findings.
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