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Impact of hypothermia level on neurological and renal outcomes in emergency aortic surgery: a single-centre experience.

Perfusion · 2026-10-22

Justine Tin Nok Chan, Ibrahim Talal Fazmin, Ismail Vokshi et al.

This single-centre retrospective study compared intraoperative temperature categories in 175 patients undergoing emergency surgery for acute aortic syndrome; 89% underwent hemiarch replacement. Overall, 30-day mortality was 18.9% and stroke incidence was 19.4%. In hemiarch patients, warmer temperatures were associated with lower stroke incidence and shorter ICU stays in unadjusted comparisons. However, adjusted four-category comparisons were not statistically significant for assessed outcomes. A sensitivity analysis using a 24.0°C threshold found an independent association with reduced stroke risk (OR 0.23, 95% CI 0.08–0.64), highlighting the dependence of findings on how temperature was categorized.

Clinical bottom line

Temperature strategy was associated with postoperative outcomes, but the adjusted findings differed by categorization. These results are hypothesis-generating rather than evidence that warmer strategies prevent stroke.

Study limitation: The single-centre retrospective design leaves potential residual confounding, and the significant sensitivity analysis contrasted with nonsignificant adjusted four-category comparisons.

Read the original on PubMed

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