A prospective study of 177 cardiac-surgery patients at Tanzania’s National Cardiac Institute assessed AKI using serum creatinine changes at 24, 48, and 72 hours postoperatively. Postoperative AKI occurred in 53%, with stage I accounting for 72.9% of cases. In adjusted analyses, blood transfusion was associated with AKI (adjusted prevalence ratio 3.63, 95% CI 1.15–11.41), as was cardiopulmonary bypass exceeding 240 minutes (3.80, 95% CI 1.57–9.18). Diabetes and ASA IV status were also associated with AKI, while female sex was associated with lower AKI prevalence.
Early postoperative AKI was common in this Tanzanian cardiac-surgery cohort. The reported associations identify potential risk markers but do not establish that modifying transfusion or bypass practices would reduce AKI.
Study limitation: This single-centre observational study cannot establish causality; patient ages are unspecified, and several adjusted estimates have wide confidence intervals.
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