This retrospective, single-center study included 71 patients with acute myocardial infarction-related cardiogenic shock receiving short-term mechanical circulatory support after PCI. In-hospital mortality was 56%, while the composite of ischemic events and all-cause mortality during shock occurred in 42%. Triple therapy use decreased from 79% at support initiation to 39% by day 7. Ischemic events occurred in 8%, with no recurrent myocardial infarction or stent thrombosis observed. Major bleeding occurred in 32%, typically within 48 hours, and was more frequent among patients receiving VA-ECMO.
This cohort highlights frequent early major bleeding alongside substantial mortality in infarct-related shock requiring mechanical support. It does not establish which antithrombotic strategy offers the best balance of bleeding and ischemic outcomes.
Study limitation: The small, retrospective, single-center cohort and absence of reported adjusted regimen comparisons limit causal interpretation.
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