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Clinical significance of elevated body temperature without infection following removal of VA-ECMO.

Heart & lung : the journal of critical care · 2026-10-17

Tomoaki Nakayama, Yu Kataoka, Yuma Makimura et al.

This retrospective study evaluated 163 cardiogenic shock patients without evidence of infection undergoing VA-ECMO removal. Temperature reached at least 38.0°C within 24 hours in 58.9%, accompanied by lower systolic blood pressure and systemic vascular resistance and higher lactate. All-cause mortality was 30.2% with versus 29.9% without elevated temperature (log-rank p=0.983). Among patients with elevated temperature, a greater temperature rise, particularly at least 1.1°C, was associated with higher all-cause mortality (HR 1.968, 95% CI 1.096–3.535); the abstract did not specify the mortality follow-up duration.

Clinical bottom line

Temperature elevation after VA-ECMO removal was common but did not distinguish overall mortality in this cohort. The association between larger temperature rises and mortality within the elevated-temperature subgroup is exploratory.

Study limitation: The retrospective design limits causal interpretation, and the subgroup association requires confirmation; mortality follow-up duration was not reported.

Read the original on PubMed

AI-generated from the published abstract with automated source checks. For research discovery; consult the original paper before applying findings.