This single-centre prospective cohort examined haemodynamic disturbances and hypotension after major vascular surgery, with 89 of 100 recruited adults available for analysis. The primary outcome was hypotension within 24 hours, defined as systolic blood pressure below 90 mm Hg or a vasopressor infusion. Hypotension occurred in 20 participants (23%); severe hypovolemia and obstruction were not observed. Vasodilation and myocardial dysfunction were associated with higher adjusted marginal risks of hypotension: risk differences were 33% (95% confidence interval, 14% to 53%) and 41% (95% confidence interval, 3% to 79%), respectively.
Vasodilation and myocardial dysfunction were associated with early postoperative hypotension in this vascular-surgery cohort. These findings describe potential haemodynamic contributors rather than establish causation or benefits from targeted treatment.
Study limitation: The single-centre observational design limits causal interpretation and generalisability, and the myocardial dysfunction estimate was imprecise.
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