This retrospective cohort included 76 comatose adult cardiac-arrest survivors who underwent somatosensory evoked potential testing and brain MRI. Extensor or absent motor responses, absent EEG background reactivity, and combined cortical-subcortical MRI involvement were independently associated with absent cortical SSEPs, with odds ratios of 7.78, 5.98, and 8.52, respectively. The model had an AUC of 0.804, increasing to 0.866 with the addition of sex. These findings describe associations with an electrophysiological prognostic marker rather than directly measuring neurological recovery or survival.
Clinical examination, EEG reactivity, and MRI patterns were associated with absent SSEPs in this selected cohort. These associations do not establish that the markers can replace SSEP testing or independently predict patient-centred outcomes.
Study limitation: The retrospective, 76-patient cohort selected patients undergoing both SSEP testing and MRI; the abstract reports no uncertainty intervals for model estimates.
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