This CathPCI registry study examined intraprocedural cardiac arrest and in-hospital mortality during PCI from 2018 to 2023. Arrest occurred during 36,755 of 3,956,840 procedures (0.93%), including 0.24% of elective procedures and 1.28% of acute coronary syndrome interventions. In-hospital mortality among patients with arrest was 40.5%; among those who died, 45.4% died in the catheterization laboratory. Over time, risk-adjusted arrest incidence increased from 0.79% to 0.95% (P = 0.042), while risk-adjusted mortality declined slightly from 45.1% to 43.6% (P = 0.027).
Intraprocedural cardiac arrest was uncommon but associated with substantial in-hospital mortality. Rising risk-adjusted arrest incidence alongside slightly declining mortality provides a contemporary benchmark, not evidence for any particular prevention or resuscitation strategy.
Study limitation: The observational registry design cannot establish causality or explain the divergent trends in arrest incidence and mortality.
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