This single-center retrospective cohort included 474 patients undergoing surgery for acute type A aortic dissection between January 2005 and May 2023. Massive postoperative bleeding occurred in 87 patients (18%), who were compared with 387 patients without massive bleeding. In multivariable analysis, preoperative APTT above 34.5 seconds was associated with massive bleeding (OR 2.95, 95% CI 1.60–5.47). Higher preoperative creatinine, hypertension, and longer cardiopulmonary bypass duration were also independently associated with bleeding. Patients with massive bleeding experienced more postoperative complications.
Preoperative APTT was associated with massive postoperative bleeding after type A dissection repair. Its usefulness for prospective risk stratification remains unvalidated.
Study limitation: The retrospective, single-center design limits generalizability, and the abstract does not report the definition of massive bleeding or predictive performance.
AI-generated from the published abstract with automated source checks. For research discovery; consult the original paper before applying findings.