This retrospective study evaluated 10 consecutive patients with post-infarction ventricular septal rupture managed with Impella support; median age was 74 years. Four patients also received veno-arterial extracorporeal life support, and one underwent Impella upgrade. Scheduled repair was achieved in nine patients (90%), with a median interval from Impella initiation to repair of 8 (7, 10) days. Pulmonary artery and central venous pressures, B-type natriuretic peptide, and lactate decreased before repair, while non-CNS SOFA scores increased. Organ support requirements and device-related complications were also observed during bridging.
This small series documents achievement of scheduled repair in most patients, alongside improving haemodynamic measures but worsening SOFA-defined organ dysfunction. It does not establish comparative benefit for an Impella-bridge strategy.
Study limitation: The retrospective, 10-patient series lacked a comparator, limiting causal interpretation and assessment of comparative clinical outcomes.
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